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Ultrasound Anomaly: Amniotic Fluid Index (AFI) vs. Deepest Vertical Pocket (DVP)

Introduction

The assessment of amniotic fluid levels during pregnancy is crucial for fetal well-being. Two main methods are employed: Amniotic Fluid Index (AFI) and Deepest Vertical Pocket (DVP). While both approaches aim to estimate amniotic fluid levels, they differ in methodology, sensitivity, specificity, and clinical implications.

 

Amniotic Fluid Index (AFI)

Definition:

  • The AFI is the sum of the maximum vertical depths of amniotic fluid in each of the four uterine quadrants. The quadrants are created by dividing the uterus using the linea nigra (longitudinal) and a transverse line through the umbilicus.

Normal Range:

  • 5–25 cm:

    • Low normal: 5–8 cm.

    • Normal: 8–25 cm.

  • <5 cm: Indicates oligohydramnios (insufficient amniotic fluid).

  • >25 cm: Indicates polyhydramnios (excessive amniotic fluid).

Utility:

  • Widely utilized in fetal biophysical profiles (BPP).

  • Peaks at 32–34 weeks of gestation, decreasing as pregnancy progresses.

Advantages:

  • Sensitivity: Effective in detecting fluid volume changes, especially decreases.

  • Provides a comprehensive overview of overall amniotic fluid volume.

Disadvantages:

  • Over-diagnoses oligohydramnios, which can lead to unnecessary interventions like induction or cesarean delivery.


 

Deepest Vertical Pocket (DVP)

Definition:

  • Measures the depth of the single largest vertical pocket of amniotic fluid free from umbilical cord and fetal parts.

Normal Range:

  • 2–8 cm:

    • <2 cm: Oligohydramnios.

    • >8 cm: Polyhydramnios.

Utility:

  • Often used as an alternative or adjunct to AFI in amniotic fluid assessment.

Advantages:

  • Specificity: Reduces over-diagnosis of oligohydramnios compared to AFI.

  • Easier and faster to perform in clinical practice.

Disadvantages:

  • May miss small or localized changes in amniotic fluid distribution.


 

Comparison Between AFI and DVP

Aspect

AFI

DVP

Method

Summation of fluid pockets in four quadrants.

Single deepest pocket measurement.

Normal Range

5–25 cm

2–8 cm

Sensitivity

Higher sensitivity for oligohydramnios.

Lower sensitivity.

Specificity

Lower specificity; prone to overdiagnosis.

Higher specificity.

Overdiagnosis

More frequent.

Less frequent.

Use in BPP

Frequently included.

Sometimes preferred for simplicity.

Outcome Prediction

Controversial; study results vary.

Controversial; study results vary.

Clinical Implications

Oligohydramnios:

  • AFI: Likely to detect more cases due to higher sensitivity, potentially leading to over-treatment.

  • DVP: Provides a conservative approach, reducing unnecessary interventions.

Polyhydramnios:

  • Both methods identify excess amniotic fluid well. However, DVP may miss localized pockets of excess fluid due to its focused measurement.


 

Conclusion

The choice between AFI and DVP depends on clinical context, the clinician’s expertise, and equipment availability. AFI offers a broader picture of fluid volume but may overestimate abnormalities, whereas DVP provides simplicity and specificity, reducing false positives for oligohydramnios. Integrating both methods when necessary can enhance diagnostic accuracy and guide appropriate management.

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